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International journal of molecular sciences , 19 (7), 1987

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During acute inflammation, pro-inflammatory M1-like macrophages accumulate in the liver, characterized by elevated expression of the NAD +degrading enzyme CD38 and increased CD38-dependent NADase activity, leading to reduced tissue NAD + levels (Stahl et al

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Meal schedule dependent experiment Based on the results, we selected the 1 g/kg dose of Ex which reduced food intake without observable side effects, and went on to investigate the hypothesised meal schedule dependent effects of Ex in all four possible meal schedule conditions (see Fig

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