However, there were no statistical differences in PKA ( P = 0.3573), p-PKA ( P = 0.2439), CREB ( P = 0.7447) or p-CREB ( P = 0.3302) expression levels between the OA and OA + saline groups
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The dosages ranged from 0.5 mg-1 mg
Western blot analysis demonstrated that exposure to rotenone for 60 days resulted in a strong inhibition of Nrf2 expression, which was profoundly restored by co-administration of sulforaphane (50 mg/kg), in the cerebral cortex and striatum, respectively (Fig