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or by enzymatic reactions involving cytochrome P450 enzymes or cholesterol-25-hydroxylase (CH25H)

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Next, after being exposed to 0, 100, 200, and 300 M H 2 O 2 for 24 h, a dose-dependent decrease in chondrocyte viability was observed, with significant decrease starting at 200 M H 2 O 2 (Fig

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