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Post-marketing surveillance has not identified a consistent hepatotoxicity signal, though the FDA Adverse Event Reporting System (FAERS) contains some reports of hepatobiliary adverse events where causality has not been established

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Sequences of the primers used for the GSTM2 RNAi experiment were referred to study of Huenchuguala 48

Some experts have criticized the increased use of the drugs as a potentially damaging extension of diet culture