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30, 34 The effect of redox dysregulation on the brain has been studied in transgenic mice with a deletion of the modifier subunit of glutamate cysteine ligase (that is, Gclm -KO mice), which leads to a 70% decrease in GSH brain levels and several schizophrenia-related phenotypes

The views expressed are those of the authors and not necessarily those of the NIHR, the UK MRC, the UK NHS or the UK Department of Health

Fuchs BC, Bode BP

Moreover, before and after IFO 400 mg per kg, through the intraperitoneal route, mesna with a dose of 80 mg per kg was subcutaneously administrated and gingerols 25 mg per kg was orally administrated

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