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An additional factor contributing to the persistent weight loss triggered by cagrilintide, without a concomitant anorectic response, could be attributed to its impact on energy expenditure

Although the pathophysiology of BBS is incompletely understood, previous research has elucidated that the obesity and hyperphagia is likely due in part to impaired MC4R pathway activity, suggesting that a MC4R agonist could be of potential therapeutic benefit

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Some people report feeling improvements in their sleep quality or a sense of calm within the first couple of weeks