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We show here that in this nematodes distal germline, type IV collagen (COL IV) levels in the basement membrane surrounding the germline stem cell (GSC) niche, likely through increasing the gonad basement membranes stiffness, promote GLP-1/Notch receptor activation in adjacent GSCs

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Translational Perspectives on GLP-1R Modulation in AUD A growing body of translational research highlights the therapeutic potential of GLP-1R agonists in AUD, bridging mechanistic findings from animal models with genetic and neurobiological data in humans

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