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Brian: I want to clarify in terms of different roles

Rothenbacher, D., Primatesta, P., Ferreira, A., Cea-Soriano, L

Only Melanotan 1 (afamelanotide) has received regulatory approval for erythropoietic protoporphyria (EPP) on the basis of phase III RCT data

However, tirzepatide also targets glucose-dependent insulinotropic polypeptide (GIP) receptors, which affect resting insulin levels

Clinical studies on Trulicity found that it reduced A1C by 1.3 to 1.6%

According to American Thyroid Association guidelines, treatment is typically initiated when TSH rises above 10 mIU/L or when TSH is between 4.5-10 mIU/L with symptoms or positive thyroid antibodies