Tracy Zvenyach, director of policy strategy and alliances at the Obesity Action Coalition, a nonprofit advocacy group
This is expected, not a sign that the treatment has failed
The primary benefits of liraglutide include: Clinically meaningful weight loss (6 to 8% average, up to 10%+ in early responders) Improved glycemic control and HbA1c reduction in type 2 diabetes Demonstrated cardiovascular risk reduction (13% reduction in MACE in the LEADER trial) Reduced progression from prediabetes to type 2 diabetes Approved for adolescents aged 12+ (obesity) and children aged 10+ (diabetes) The longest safety track record of any GLP-1 receptor agonist How It Works GLP-1 Receptor Activation Liraglutide functions as a potent agonist at GLP-1 receptors distributed throughout the pancreas, brain, heart, and gastrointestinal tract
The process involves a combination of reduced caloric intake, hormonal balance, improved insulin activity, and behavior changes over time
None of these are likely in the near term
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