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Five impact areas are identified: glycemic profile, inflammation, oxidative stress, lipid profile, and hormonal profile, each linked to metabolic and endocrine alterations characteristic of PCOS

Beyond immediate glycemic control, GLP-1 signaling enhances -cell function, promotes -cell proliferation, and inhibits apoptosis in preclinical models [53]

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Biotechnol 2011, 164 (7), 9911022

Sulphonylureas (e.g., gliclazide, glimepiride): These medications stimulate insulin release and carry an inherent hypoglycaemia risk

The Energy Balance Equation Weight loss requires a caloric deficit