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This means the drug does not hit peak levels and stay there permanently

Instead of making identical copies of the weight loss drugs, Empower and other compounders combine a GLP-1, either semaglutide or tirzepatide, with vitamin B12, change the dosage strength, or offer different delivery methods

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GLP-1R activation increases the recruitment of the fission protein Drp1 to mitochondria and enhances mitophagy, thereby removing damaged organelles and protecting tissues from oxidative stress (Torres et al., 2016)

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GLP-1 receptor activation slows gastric emptying (making food stay in the stomach longer, which extends satiety), reduces glucagon secretion (lowering blood sugar), and acts on hypothalamic neurons to reduce hunger drive