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Originally developed to treat Type 2 diabetes, these medications are now recognized for their ability to aid in weight loss by mimicking a hormone called GLP-1 (glucagon-like peptide-1)

1 The dose of Ocrevus of 600 mg every 6 months begins after the initial dosing period, which consists of two 300 mg IV infusions administered 2 weeks apart

531 Both SIRT1 and SIRT3 exert their function through PGC-1, which acts as a modifier in HD and ALS patients and other models

Excess weight promotes the development of a wide range of pathologies (insulin resistance, hypertension, chronic inflammation, dyslipidemia), which increase the risk of complications such as type 2 diabetes, cardiovascular disease, hepatic steatosis, several types of cancer and reduce life expectancy

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