Proteinprotein interactions: developing small-molecule inhibitors/stabilizers through covalent strategies
However, various limitations of these two biomarkers, including low sensitivity and specificity, delayed rise in plasma because of functional reserve, and extrarenal clearance, demand for novel renal biomarkers to early detect and monitor drug-induced nephrotoxicity with high specificity and sensitivity
Anemia caused by underlying diseases may manifest symptoms of that disease instead of anemia
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Signs and symptoms depend on the severity of depletion, ranging from anaemia and fatigue to bone marrow suppression and impaired cognition
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