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Given the coupling between copper and energy status (e.g copper is a cofactor at Complex IV of the ETC) and how intensely metabolically active neurons are, it seems like short-term IP GHK-cu in the brain is acting analogously to the copper ionophore elesclomol in Tregs

10.1016/j.chemphyslip.2013.10.011 83 PengY.AoM.DongB.JiangY.YuL.ChenZ.et al (2021)

The published research literature documents KPV effects on inflammatory cytokine production, mast cell activation, and inflammatory bowel pathway signaling

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Cells were spun down at 100 rcf for 3 min and each single microwell contained at least 5000 cells, cultured in E8F medium (without antibiotic) containing 10 M ROCK inhibitor Y-27632 (10 mM stock, Stemcell Technologies, USA #72304)

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