requires clinical setting, higher cost, time-intensive
J Clin Endocrinol Metab (2001) 86:47538.10.1210/jcem.86.10.7885 16 TschopMSmileyDLHeimanML
In some cases, these drugs were studied at dose strengths that may not be available with off-label use
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The choice of agents should be guided mainly by their presumed effectiveness and by potential or actual adverse effects