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doi: 10.1007/s13238-018-0549-0, 25 WeiH.WuJ.WangH.HuangJ.LiC.ZhangY.et al
After 48 h, cells were washed with phosphate-buffered saline, and test compounds ( 50ac , at concentrations of 0.1, 1 or 10 M with 1% dimethyl sulfoxide (DMSO)
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It is the only peptide in this class with human clinical data: the NERVARA trial (Phase 2, NCT02039687) studied its effect on diabetic neuropathy
Despite the clear beneficial effects of incretin-based therapies, there are also concerns reported in respect of the risk for long-term complications like pancreatitis (115)
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