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Nawrocki WJ, Tourasse NJ, Taly A, Rappaport F, Wollman FA (2015) The plastid terminal oxidase: its elusive function points to multiple contributions to plastid physiology

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The inclusion of a MANCOVA with patient as a fixed effect partially addresses this issue by accounting for between-subject variability, and the convergence of findings across analytic approaches strengthens confidence in the primary results

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This increased risk has led researchers and regulators to urge caution for patients with existing eye disease