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Large-scale prospective clinical trials conducted in CD patients have found that supplementation with PUFA may worsen IBD symptoms, indicating disrupted gut homeostasis [294]

Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism

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Phytosterols: from preclinical evidence to potential clinical applications

It activates both GLP-1 and glucagon receptors, with the glucagon component being particularly relevant for hepatic fat metabolism -- a key differentiator that has driven its MASH development program