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223 SIRT4 modulates mitochondria energy homeostasis and longevity based on its lysine deacetylase, lysine deacylase, lipoamidase and ribosylase activity

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Insights into immune dysregulation, cholestatic injury, and bile acid homeostasis have facilitated the development of agents targeting specific pathways, including FXR agonists, PPAR agonists, and immunomodulators

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