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MuRF-1 and MAFbx/Atrogin-1 (E3 ubiquitin ligases mediating myofibrillar proteolysis) are suppressed 3442% in IGF-1 LR3-treated myotubes under dexamethasone-induced atrophy conditions (1 M Dex, 24 h), demonstrating anti-atrophy activity via Akt-dependent FoxO1/FoxO3a phosphorylation (nuclear exclusion +3844%)

Murata, H., Hruz, P

Both LEVs and SEVs demonstrated a superior whitening impact on melanoma cells when compared to arbutin, a frequently used positive control, with LEVs being particularly effective

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