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Afferent fibers, which constitute 80% of vagal nerve fibers, transmit mechanical, chemical, and immune signals from the gut to the CNS, whereas efferent fibers (20%) convey central commands to the gut, modulating digestive function and immune responses ( 2.1.2 Bidirectional regulatory mechanisms The bidirectional regulatory mechanisms of the MGBA are manifested through bottomup pathways, whereby gut microbiota influence brain function, and topdown pathways, whereby the CNS modulates gut microecology (Mayer et al., 2022)

Scientific reports 13(1), 2023

They still need to move their bodies

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This translates to roughly 50 grams of protein per day, for a person who weighs 100 pounds