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(Gastroenterology, 2008) reported PepT1-mediated uptake in human epithelial and immune cell lines with reduced NF-B activation and attenuated experimental colitis in mice
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It must also replicate the specific structural modification that constitutes the bio-betterthe PEGylation, glycoengineering, or bispecific architecturewhich is typically more technically complex than developing a biosimilar of a conventional monoclonal antibody
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