No variable showed significant effects
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1c,d) and was previously suggested as a candidate for a potential activator site, first, because its positive charge might stabilize or bind GSH as GS , and, second, because of its evolutionary conserved position that is equivalent to the GSH-interacting catalytic residue of glutathione transferases 3
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In fact, ROS facilitates TLR4 trafficking to the plasma membrane, thereby promoting the TLR4 activity (83, 84)
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