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2.4.2 Dysbiosis of gut microbiota in MS In patients with MS, it was found that the composition of their microbiota was relatively reduced from that of healthy individuals

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Since NMN (nicotinamide mononucleotide) was previously reported to increase the levels of NAD + by acting as the precursor for NAD + 27 , we investigated whether NMN treatment would have therapeutic impact on diseased UMNs