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Cytoplasmic, bioavailable zinc is essential for IL-1 production in activated human monocytes and macrophages, acting downstream of glycolysis, which is induced by the mammalian target of rapamycin complex 1 (mTORC1)

Archived from the original (PDF) on 22 February 2014

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Both MTX and 7-hydroxy MTX are excreted by the kidneys, and a small part is also excreted in the bile (Reference Saka and Aouacheri2)

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