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As depicted in Figure 3, we propose that the lactate-lactylation axis drives PH pathogenesis through five key mechanisms: PASMC proliferation, immune-inflammatory responses, pulmonary fibrosis, abnormal vasoconstriction, and PASMC ferroptosis

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Deficiency leads to secondary hyperparathyroidism, increased bone turnover, and elevated fracture risk

10.1038/s41467-023-37464-2 139 NortonC

It is also, in the specific arena of stimulating scalp hair growth, a compound whose human clinical record is thin, indirect, and easily overstated by the wellness market that surrounds it