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Even a slight miscalculation can affect results or cause unwanted side effects

doi: 10.1210/jc.2019-00281 54 ShiLWeiXWuBYuanCLiCDaiYet al

Ruvolo P, Ma H, Ruvolo V, Mu H, Shober W, Yasuhiro T, Yoshizawa T, Gallardo M, Zhang X, Khoury JD, Cortex JE, Andreeff M , Post SM

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The cycle involves the transfer of a methyl group (CH3) from one molecule to another, which is facilitated by enzymes that are dependent on certain vitamins and nutrients, such as folate, vitamin B12, and SAMe