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Weight changes from GLP-1 therapy may require adjustment of levothyroxine doses, necessitating close thyroid function monitoring

GLP-1RAs thus prevent the occurrence of retinal damage associated with oxidative-stress-induced activation of glial cells and collectively foster a healthy retinal microenvironment by virtue of preventing cellular overexertion [94, 100]

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Liraglutide, 97% sequence identity to native GLP-1, is obtained by derivatizing GLP-1 with a fatty acid (128)

Circulation 129 , 587597 (2014)

In the 1960s, manufacturers introduced short-term weight-loss medications such as phentermine, benzphetamine, and diethylpropion, but researchers did not collect long-term safety data (8)