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Once glutathione neutralises a free radical, it changes converting from its active "reduced" form (GSH) into an oxidised, "used-up" form (GSSG)

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5.3 Diabetic Retinopathy Complications In a pooled analysis of glycemic control trials with RYBELSUS, patients reported diabetic retinopathy related adverse reactions during the trial (4.2% with RYBELSUS and 3.8% with comparator) [see Adverse Reactions (6.1)]