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Because this mechanism is glucose-dependent (only activated when blood glucose levels are elevated), DPP-4 inhibitors do not carry the risk of hypoglycemia, unlike traditional insulin secretagogues

Patients should be advised that Mounjaro is not recommended during pregnancy, and effective contraception should be used during treatment

ER36-positive cells are overlapped with ALDH1 high subpopulation, whereas not predominant in CD44 + /CD24 /low /ESA + cells in flow cytometry assays (data not show)

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Bode SF, Egg M, Wallesch C, Hermanns-Clausen M

The standard schedule raises the dose every four weeks, from 2.5 mg through 5, 7.5, 10 and 12.5 mg up to the maintenance dose of 15 mg