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doi: 10.3389/fnut.2021.660150 Received 28 January 2021 Accepted 16 April 2021 Published 13 May 2021 Volume 8 - 2021 Edited by Moacir Marocolo, Juiz de Fora Federal University, Brazil Reviewed by Luke Colin McIlvenna, University of Birmingham, United Kingdom

Clinical Trial Insights In a Phase 2 clinical trial published in The New England Journal of Medicine , Retatrutide demonstrated remarkable efficacy: Participants with obesity (without diabetes) experienced up to 24.2% reduction in body weight over 48 weeks, surpassing results seen with existing medications