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The trial involved 636 participants who were randomly assigned to receive tirzepatide (5 mg, 10 mg, or 15 mg) or dulaglutide (0.75 mg) once a week for 52 weeks

The significant weight loss observed in patients was, initially, a powerful and very welcome side effect

The second uncomfortable truth: most dosing errors happen at reconstitution, not administration

Treatment with A alone resulted in reduced neurite numbers and length compared to controls, and the additional treatment with -HB reversed A toxicity, suggesting that -HB could potentially play a neuroprotective role against A toxicity

This way it helps in exercise recovery

Lastly, for those who are eligible, metabolic/bariatric surgery should remain part of the conversation, as it is one of the most effective and durable obesity treatments we have