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Another, larger meta-analysis reported no reduction in HF hospitalizations but did observe improvements in tissue Doppler measurements and diastolic function, suggesting possible benefits in diastolic HF [33]

It causes abnormal connections between arteries and veins and in addition to nosebleeds, it can present with symptoms such as anemia, headaches, red spots on the skin, seizures, and shortness of breath

Eligibility requires specific BMI thresholds (30 kg/m or 27 kg/m with comorbidities) and previous weight loss attempts, not food noise alone

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Persistent vomiting, inability to tolerate oral intake, or signs of bowel obstruction require immediate evaluation