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Effect of alpha-tocopherol and beta-carotene supplementation on macrovascular complications and total mortality from diabetes: results of the ATBC Study

The cardiovascular benefits of GLP-1-RAs arise primarily through indirect systemic mechanisms, with limited evidence supporting direct effects on cardiomyocytes ( Figure 1 )

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As interest in this enzyme grew, researchers began developing experimental compounds capable of interacting with NNMT in controlled laboratory environments