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Another extensive study detected different post-translationally modified -synuclein in the lysate of red blood cells such as different types of phosphorylated -synuclein apart from pS129, nitrated or glycated or small ubiquitin-like modifier or SUMO-ylated -synuclein, and showed that phosphorylated, nitrated, and glycated -synucleins were elevated and SUMO-ylated -synuclein was decreased in PD patients with respect to that in controls (Miranda et al., 2017)

They're involved in processes such as tissue repair, immune activity, and communication between cells

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Disturbance of copper metabolism is the primary cause of monogenic Wilsons and Menkes diseases 1 and it is also involved in progression of inflammation, cancer, atherosclerosis 2 and many neurodegenerative diseases including the Alzheimers disease 3

GST can be used as targets for cancer therapy [2]

doi: 10.1590/s0004-2803.201900000-36