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CTLA-4 exists as a gene with several isoforms, and the inheritance of some of them is associated with a higher incidence of GD (132-137), and increased production of anti-TPO and anti-Tg antibodies (138)
The vast majority of these 57 papers did not indicate the retraction of the original article, nor did the authors seem to be aware of it
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To verify the effect of HZRG on BA absorption, we first detected the tight junction proteins that are associated with intestinal permeability, and found that the expression of tight junction protein Occludin and Claudin was decreased in NASH mice, whereas HZRG intervention counteracted the decrease (Figure 5D)
The ratio of the peak area of BsNbs to uncombined free monomers in the chromatogram was utilized as a metric for comparing the reaction efficiency of the dual antibody linkage across different groups