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However, sudden vision loss should always be treated as urgent

In a 2023 randomized trial published in the ClinicalTrials.gov database, participants experienced an average of 1724% total body weight reduction after 48 weeks of treatment

The limit defining the existence of MHE is 4 points

These factors extend the network of DAMPs signaling beyond the classical receptors and can further modulate immune cell responses in the postoperative period (for example, IL-33 can drive type 2 immunity and might aid in resolution of injury, whereas HMGB1 sustains inflammation and also promotes immunosuppression in late phases) (53)

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2023;147(8):e93621