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IGF-1 Elevation Increased growth hormone stimulates the liver to produce more IGF-1 (insulin-like growth factor 1), which mediates many of GH's downstream benefits including muscle growth, tissue repair, and fat metabolism
It would be important to reassess this pattern now with more widespread adoption of GLP-1s for obesity alone, since the study period ended in 2022
doi: 10.4093/dmj.2014.38.1.25 96
Plan for longevity GLP-1s must be integrated with lifestyle changes and long-term care
External resources Dietary supplement considerations during GLP-1 receptor agonist treatment: a narrative review (PMC) Effect of creatine supplementation on kidney function: systematic review and meta-analysis (PMC) A short review of the most common safety concerns regarding creatine ingestion (PMC) Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes (NEJM) In case I do not see you, good afternoon, good evening, and good night