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It can help improve mobility, reduce pain caused by muscle stiffness, and enhance the quality of life for patients with chronic spasticity

Therefore, basic research to clinical transformation remains the rate-limiting step in the development of treatment strategies for ASD, and the degree of heterogeneity may be considered, which may obscure the effect of experimental treatments

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Testing MTHFR and other relevant genetic markers can identify these individuals, though routine genetic testing for b12 supplementation decisions remains controversial

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