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Combined these results indicated that NP4 catalyzes the generation of H 2 O 2 in tumor cells, which diffuses outside the cells and activates macrophages, thereby triggering immune responses

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These results suggest FOXO4DRI clears senescent cells in the PF model and regulates senescenceassociated genes

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Thus, erythrocytes can be model cells for the management of sepsis/septic shock to improve the outcome of patients [111]

In other words, selenium helps glutathione do its thing