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Potential Benefits of L-Carnitine Supports energy metabolism Popular among endurance athletes Commonly used before training Available in capsules, liquids, and powders Who May Prefer L-Carnitine

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Ethics declarations Conflict of interests AA received honoraria for speaker activities, for serving on advisory boards, or consultancy from AstraZeneca, Boehringer Ingelheim, Eli Lilly, Amarin, Bruno Farmaceutici, Amgen, Novo Nordisk, and Sanofi

Moreover, loss-of-function mutations of succinate dehydrogenase (SDH) increase cellular succinate level, which inhibits DNA demethylation and contribute to tumorigenesis [62,63]