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In this regard, it has been shown that SSTR5 exerts antiproliferative and antisecretory effects in somatotroph by coupling with the inhibitory G protein G oA , independently of cAMP reduction, suggesting a dissociation between these pathways (11, 42)

(2001) 2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity

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Authors: JL Flanagan et al

As the dimerization of Met is a critical initial event for intracellular tyrosine transphosphorylation, our data indicate that the bell-shaped responses in phosphorylation of Met (Fig