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Research suggests these adverse events may occur in 40 to 85% of people
Source: NEJM 2023 Safety profile: The most common adverse events were gastrointestinal (nausea 58%, diarrhea 39%, vomiting 32% in the 12 mg group)
The resulting lower risk of end-stage renal disease (ESRD), renal insufficiency, or death from renal and cardiovascular causes in this subset indicated that canagliflozin may be an effective treatment for cardiovascular and renal protection [30]
Will GLP-1s keep me from getting cancer
The full GI impact often peaks around days three to seven and then progressively subsides over the following two to three weeks.
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