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Additional in vivo and in vitro studies are necessary to verify the involvement of ferroptosis in HD-specific pathologic mechanisms and development

TABLE 2 Commonly used MD simulation tools

386 Increasing levels of nicotinamide adenine dinucleotide (NAD + ) precursors can improve symptoms of acquired muscle dysfunction by activating mitochondrial metabolism

Survival curves were generated with Kaplan-Meier plots

Conventional Treatments If the response to conventional treatments is poor or to boost local effect, intratympanic injection (injecting through the eardrum into the middle ear) is used