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In this medical case, the immune system produces antibodies known as thyroid-stimulating immunoglobulins (TSI) that mimic the action of thyroid-stimulating hormone (TSH)

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Endocrinology (2006) 147(3):130613

Therefore, it is tempting to speculate that the hps locus encodes parts of a novel synthase-dependent system that secretes EPS slime using PilQ as the OM gate

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A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis