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Signal transduction by reactive oxygen species
FXR and SHP function as nutrient-sensitive switches that activate or repress autophagy on the basis of the tissue environment and metabolic signals, particularly in the liver and intestine
This could, however, in turn exacerbate unequal patient access issues
doi:10.1002/mgg3.745CrossRefGoogle ScholarPubMed Beversdorf, DQ, Carpenter, AL, Miller, RF, Cios, JS, Hillier, A
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The AIF pathway, together with increased levels of cleaved caspase 3, is recognized as the main inductor of apoptosis in the damaged brain of neonatal rodents 38 , even if their action becomes less pronounced once the brain matures 39
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