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(5.6) Hypersensitivity Reactions: Anaphylactic reactions and angioedema have been reported postmarketing

Sample concentration (particle/mL) and size (nm) were calculated using NTA software

Physical exam and basic labs are reserved for concerning patterns

This is especially important for individuals under 18 years of age

Currently, except for the activation of death receptor (e.g., FAS and TNFR1), necroptosis can be triggered by multiple stimuli, including activation of Toll-like receptor (TLR) 3 [98], TLR4 [99], nucleic acid sensors (e.g., Z-DNA-binding protein 1, ZBP1, also known as DNA-dependent activator of interferon-regulatory factor (DAI)) [100,101,102]