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Cartilage & Joint Protection Because DSIP is often studied for sleep regulation , it is natural to compare it with melatonin , the most widely used sleep supplement: AOD-9604 demonstrated chondroprotective effects in models of cartilage degradation. May reduce proteoglycan loss and support collagen maintenance

Patients in the clinical trials, who all have diabetes and/or obesity, also had fewer complaints about nausea and diarrhea

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Acknowledgements Financial support was provided by NSF Atmospheric Chemistry Program (Award # AGS-2128133) to D.C.O.T