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doi:10.1016/j.molmet.2019.09.010 FDA Approves New Medication for Chronic Weight Management

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This distinction argues for careful long-term monitoring in peptide development programs, rather than suggesting that such risks are categorically greater than those of other modalities

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Most GLP-1 agonists (semaglutide, liraglutide, dulaglutide, tirzepatide) do not require dose adjustment for mild-to-moderate renal impairment, though caution is warranted in severe renal impairment