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This longer duration of action allows for less frequent use in research protocols, reducing the number of interventions needed and minimizing stress on research subjects

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Some people experience zero GI symptoms beyond mild appetite reduction

Although the acute intravenous administration of amlodipine decreases arterial blood pressure and increases heart rate in hemodynamic studies of patients with chronic stable angina, chronic oral administration of amlodipine in clinical trials did not lead to clinically significant changes in heart rate or blood pressures in normotensive patients with angina

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